Recombinant Human Growth Hormone (rhGH), also known as Somatropin, is a 191-amino acid single-chain polypeptide that is structurally identical to endogenous growth hormone produced by the anterior pituitary gland. It is synthesised via recombinant DNA technology and belongs to the somatotropin family of hormones. Growth hormone plays a central role in somatic growth, cellular regeneration, and the regulation of metabolism across multiple organ systems. It exerts its effects both directly and indirectly through the stimulation of Insulin-like Growth Factor-1 (IGF-1) in the liver and peripheral tissues.
Use Cases
In research settings, recombinant HGH is reconstituted with bacteriostatic water and administered via subcutaneous or intramuscular injection. It is studied in the context of growth regulation, body composition modelling, metabolic signalling, IGF-1 axis research, and cellular repair mechanisms.
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