MELANOTAN II

Melanotan 2 is a synthetic cyclic heptapeptide (Ac-Nle-c[Asp-His-D-Phe-Arg-Trp-Lys]-NH₂) that functions as a potent nonselective melanocortin receptor agonist. It is employed in receptor binding and signal transduction studies exploring MC1R–MC5R-mediated cAMP activation and GPCR desensitization mechanisms. MT-II provides a research model for peptide–receptor pharmacology and neuroendocrine signaling dynamics.

For research use only. Not for human consumption.

References:
Hadley ME et al., Peptides, 1996 17(4):593–596
Mountjoy KG et al., Endocr Rev, 1994 15(2):135–155
Hruby VJ et al., Peptides, 2000 21(3):423–438