{"product_id":"genovare-peptides-kpv-30-mg-pen","title":"Genovare Peptides | KPV 30 mg Pen","description":"\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003e\u003cstrong\u003eWhat It Is\u003c\/strong\u003e KPV (Lys-Pro-Val) is a synthetic tripeptide derived from the C-terminal end of alpha-Melanocyte-Stimulating Hormone (α-MSH), retaining the parent molecule's anti-inflammatory activity without its broader hormonal effects such as pigmentation changes. KPV exerts its anti-inflammatory effects by binding to melanocortin receptors MC1R and MC3R on immune cells, inhibiting activation of the NF-κB transcription factor pathway, and reducing the release of pro-inflammatory cytokines including TNF-α, IL-6, and IL-1β. A notable property of KPV is its stability in the gastrointestinal environment: it is small enough to be absorbed orally via the PepT1 transporter in intestinal epithelial cells, making it uniquely suited to gut-targeted anti-inflammatory research. Preclinical models have demonstrated activity in colitis, gut barrier function, and dermatological inflammation.\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003e\u003cstrong\u003eHow It Is Used\u003c\/strong\u003e KPV is administered via subcutaneous injection or oral formulation depending on the research model. Applications include inflammatory bowel disease modelling, gut barrier function research, dermatological inflammation studies, melanocortin receptor pharmacology, and systemic anti-inflammatory pathway investigations.\u003c\/p\u003e","brand":"Genovare","offers":[{"title":"Default Title","offer_id":47357312598165,"sku":null,"price":685.0,"currency_code":"AED","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0752\/0282\/2293\/files\/WhatsAppImage2026-05-20at04.14.07_2.jpg?v=1779270779","url":"https:\/\/genovarepharma.com\/products\/genovare-peptides-kpv-30-mg-pen","provider":"Genovare Pharma","version":"1.0","type":"link"}